| J.J. McCarthy | MIN | 3189 | Caleb Williams | CHI | 3122 | Joe Burrow | CIN | 2880 | Josh Allen | BUF | 2745 | Lamar Jackson | BAL | 2669 |
| Josh Jacobs | GB | 995 | Jaylen Warren | PIT | 822 | Joe Mixon | NYG | 810 | Travis Etienne Jr | JAX | 807 | Christian McCaffrey | SF | 783 |
| Rome Odunze | CHI | 1130 | Stefon Diggs | HOU | 908 | Puka Nacua | LAR | 886 | Justin Jefferson | MIN | 828 | Chris Godwin | TB | 819 |
| Brock Bowers | LV | 705 | Hunter Henry | NE | 636 | Devin Payne | NYJ | 632 | Pat Freiermuth | PIT | 613 | Dalton Kincaid | BUF | 609 |
Defensive Leaders
| Alim McNeill | DET | 8.0 | Braden Fiske | LAR | 7.5 | Derrick Brown | CAR | 7.5 | Shaquille Johnson | TB | 7.0 | Maxx Crosby | LV | 6.5 |
| Dillon Northcutt | CLE | 67 | Kyzir White | TB | 62 | Jamin Davis | WAS | 59 | Micah McFadden | NYG | 58 | Jeremiah Owusu-Koramoah | CLE | 58 |
| Kool-Aid McKinstry | NO | 6 | Martin Emerson Jr | LV | 5 | Taron Johnson | BUF | 5 | DeShon Elliott | JAX | 4 | Trevon Diggs | DAL | 4 |
| Patrick Queen | PIT | 3 | Beanie Bishop Jr | PIT | 3 | Micah Parsons | DAL | 2 | Trent Yates | CAR | 2 | Jordyn Brooks | MIA | 2 |
Special Teams Leaders
| Ka'imi Fairbairn | HOU | 86 | Daniel Carlson | LV | 81 | Brendan Baugh | NO | 76 | Brayden Narveson | NYG | 74 | Justin Tucker | BAL | 73 |
| Logan Cooke | WAS | 2241 | Mitch Wishnowsky | SF | 2107 | Dustin Hopkins | CLE | 1953 | Chad Schwartz | DAL | 1876 | Ryan Stonehouse | DET | 1761 |