| Marc Cohen | MIA | 3329 | Joe Burrow | CIN | 3260 | Desmond Newman | LV | 2866 | Patrick Mahomes | KC | 2816 | Jayden Daniels | WAS | 2768 |
| De'Von Achane | MIA | 1844 | Javonte Williams | DAL | 1383 | Christian McCaffrey | SF | 1377 | James Cook III | BUF | 1159 | Jaylen Warren | PIT | 1135 |
| Ja'Marr Chase | CIN | 920 | Joey Holloway | ATL | 869 | Tee Higgins | CIN | 853 | Xavier Worthy | KC | 829 | Jameson Williams | MIA | 792 |
| Brock Bowers | LV | 720 | Pat Freiermuth | PIT | 549 | Tyler Warren | IND | 542 | David Njoku | CLE | 502 | Dalton Kincaid | BUF | 489 |
Defensive Leaders
| Will Anderson Jr | HOU | 11.5 | Bradley Chubb | LAC | 10.0 | Nik Bonitto | DEN | 10.0 | Josh Hines-Allen | JAX | 9.5 | Jonathan Greenard | MIN | 9.0 |
| Dre Greenlaw | DEN | 60 | Kevin Winston Jr. | WAS | 55 | Bobby Wagner | NYJ | 54 | Daiyan Henley | LAC | 53 | JD Bertrand | ATL | 53 |
| Fred Warner | SF | 5 | Tarheeb Still | LAC | 4 | Kendall Fuller | CAR | 3 | Dru Phillips | NYG | 3 | Cam Taylor-Britt | CIN | 3 |
| DeShon Elliott | PIT | 5 | Grant Delpit | CLE | 4 | Chuck Clark | PIT | 4 | Alohi Gilman | SF | 3 | Patrick Queen | PIT | 3 |
Special Teams Leaders
| Brandon Aubrey | DAL | 92 | Cameron Dicker | LAC | 92 | Harrison Butker | KC | 87 | Riley Patterson | SF | 84 | Jake Bates | MIA | 81 |
| Corey Bojorquez | CAR | 2634 | Matthew Hayball | ATL | 2140 | Malcolm Richardson | NYJ | 2006 | Michael Dickson | SEA | 1806 | Bradley Pinion | TEN | 1761 |