| Caleb Williams | CHI | 1529 | Sam Darnold | SEA | 1489 | Jalen Hurts | PHI | 1488 | Joe Burrow | CIN | 1473 | Jordan Love | GB | 1454 |
| Bijan Robinson | ATL | 931 | Breece Hall | NYJ | 607 | Kyren Williams | LAR | 575 | Chuba Hubbard | CAR | 537 | Saquon Barkley | PHI | 518 |
| Cooper Kupp | SEA | 641 | DeVonta Smith | PHI | 604 | Tee Higgins | CIN | 503 | Malik Nabers | NYG | 497 | Garrett Wilson | NYJ | 463 |
| Tucker Kraft | GB | 356 | Kyle Pitts Sr | ATL | 346 | Chigoziem Okonkwo | WAS | 333 | Theo Johnson | NYG | 313 | Jake Ferguson | DAL | 283 |
Defensive Leaders
| Myles Garrett | LAR | 7.5 | Aaron Donald | LAR | 6.5 | Jared Verse | CLE | 6.0 | Alex Highsmith | PIT | 5.5 | Joey Bosa | NYG | 5.0 |
| Cody Barton | TEN | 33 | Alontae Taylor | TEN | 31 | Demario Davis | NYJ | 31 | Kerby Joseph | DET | 31 | Xavier Watts | ATL | 30 |
| Jalen Ramsey | PIT | 4 | Bobby Okereke | CAR | 3 | Kenny Moore II | CLE | 3 | Riq Woolen | PHI | 3 | Trent McDuffie | LAR | 3 |
| Azeez Al-Shaair | HOU | 2 | Riley Moss | DEN | 2 | Talanoa Hufanga | DEN | 2 | DeMarcco Hellams | ATL | 2 | Joey Bosa | NYG | 2 |
Special Teams Leaders
| Jake Elliott | PHI | 50 | Andres Borregales | NE | 48 | Evan McPherson | CIN | 46 | Tyler Loop | BAL | 44 | Nick Folk | ATL | 43 |
| Jeremy Crawshaw | DEN | 1659 | Logan Cooke | JAX | 1599 | Corey Bojorquez | CLE | 1562 | Ethan Evans | LAR | 1258 | Tress Way | WAS | 1154 |