| Christopher Callahan | LAR | 4226 | Brian Donahue | NYG | 3340 | Eric Medina | CLE | 2663 | Isaac Burr | PIT | 2362 | Desmond Newman | LV | 1476 |
| Reshard Archer | NE | 433 | Keon McQueen | MIN | 319 | Kadeem Carradine | BAL | 251 | Latwan Stapleton | LAR | 156 | Johnny Harding | PHI | 122 |
| J.J. Wayne | WAS | 893 | Joey Holloway | ATL | 584 | Dylan Kane | CAR | 548 | Justin Franklin | MIN | 392 | Brandon Allen | JAX | 373 |
| Kamryn Cross | MIA | 287 | Nick Gutierrez | DEN | 67 | Derek Franklin | NE | 41 | Damian Preston | JAX | 41 | Teddy Skaggs | NYG | 40 |
Defensive Leaders
| Steven Long | TB | 11.0 | Shelton Allen | HOU | 7.5 | Victor Poole | BAL | 6.0 | Terron Holloway | KC | 5.0 | Cassidy Jackson | LAC | 4.5 |
| Jimmy Smiley | IND | 64 | Shonn Clements | NO | 50 | Jerry Banks | DAL | 43 | Trevor Moulton | BUF | 41 | Glen Britt | LV | 40 |
| Jerry Banks | DAL | 5 | Shawn Chaisson | LV | 3 | Mack Smith | LAR | 2 | Antwan Sanborn | IND | 2 | Sean Brown | LAC | 2 |
| Trevor Moulton | BUF | 3 | Shawn Chaisson | LV | 2 | Manuel Romero | LAR | 1 | Steven Long | TB | 1 | Jerry Banks | DAL | 1 |
Special Teams Leaders
| Eric Bailote | ATL | 1735 | Elijah Burr | DAL | 1385 | Esteban Cruz | KC | 1260 | Mike Springs | IND | 104 | Nick Harrison | IND | 99 |