| Fernando Mendoza | LV | 1542 | Jack Strand | ATL | 570 | Behren Morton | NE | 373 | Cade Klubnik | NYJ | 197 | Drew Allar | PIT | 73 |
| Jeremiyah Love | AZ | 476 | Mike Washington Jr. | LV | 255 | Jadarian Price | SEA | 246 | Nick Singleton | TEN | 235 | Seth McGowan | IND | 108 |
| Zavion Thomas | CHI | 580 | Ted Hurst III | TB | 541 | Makai Lemon | PHI | 494 | KC Concepcion Jr | CLE | 479 | Omar Cooper Jr. | NYJ | 459 |
| Kenyon Sadiq | NYJ | 254 | Joe Royer | CLE | 137 | Justin Joly | MIA | 108 | Eli Stowers | PHI | 78 | Nate Boerkircher | JAX | 47 |
Defensive Leaders
| Cashius Howell | CIN | 4.5 | Romello Height | SF | 4.0 | Gabe Jacas | NE | 4.0 | Caleb Banks | MIN | 3.5 | Rueben Bain Jr. | TB | 3.5 |
| Josiah Trotter | TB | 35 | Avieon Terrell | ATL | 32 | Chris Johnson | MIA | 32 | Bud Clark | SEA | 30 | Genesis Smith | LAC | 27 |
| Michael Taaffe | MIA | 1 | Chris Johnson | MIA | 1 | Colton Hood | NYG | 1 | Josiah Trotter | TB | 1 | Davison Igbinosun | BUF | 1 |
| Tyler Onyedim | DEN | 2 | Josiah Trotter | TB | 2 | Caleb Banks | MIN | 1 | Colton Hood | NYG | 1 | Jordan van den Berg | CHI | 1 |
Special Teams Leaders
| Trey Smack | GB | 58 | Dominic Zvada | NYG | 54 | Drew Stevens | WAS | 50 |
| Ryan Eckley | BAL | 1182 | Brett Thorson | MIN | 757 | Tommy Doman Jr | BUF | 459 |