| George Johnson | LAR | 4351 | Daniel Trainor | HOU | 1078 | Chad Bolton | LV | 976 | Eric Scott | CHI | 184 | Christian Phillips | DEN | 100 |
| Deionte Rich | HOU | 1868 | Daniel Hyde | ARI | 861 | Damarr Perkins | GB | 275 | Keon McKee | CIN | 262 | DeMarcus Davis | BAL | 208 |
| Emmett Brown | LAR | 874 | Devontae Carey | CHI | 702 | Sergio Jones | SF | 454 | Kevin Allison | MIA | 447 | Dylan Madden | CIN | 402 |
| Kevin Allison | MIA | 447 | Dylan Madden | CIN | 402 | A.J. McKinley | CHI | 390 | Josh Van Buren | NE | 350 | Kendrick Talley | ARI | 275 |
Defensive Leaders
| Silas Holloway | SEA | 8.0 | Nathan Rice | ARI | 5.5 | Ben Banks | GB | 5.0 | Adam Boyd | TEN | 4.5 | Phillip Ward | LAC | 3.0 |
| Malcolm Izzo | TB | 77 | Larry Greene | KC | 73 | Alex Holmes | NO | 67 | Jamie Cooper | DET | 60 | Johnnie Cline | DEN | 55 |
| Darrius Richards | CHI | 4 | Lance Mitchell | ARI | 3 | Larry Greene | KC | 2 | Johnnie Cline | DEN | 2 | Tommy Whittington | IND | 2 |
| Quincey Basnight | KC | 2 | Kahlil Carrington | NYG | 1 | JaMichael Murphy | TEN | 1 | Joseph Kelley | LV | 1 | Ben Daniels | JAX | 1 |
Special Teams Leaders
| Bradley O'Connell | WAS | 118 | Matt Campbell | SF | 92 | Joe Nicholson | PIT | 65 | Kirk Cunningham | MIN | 46 |
| Joe Washington | NO | 2285 | Daniel Winters | MIA | 598 | Clifton Wallace | DET | 246 | Nick Rinehart | IND | 150 |